RSC Advances 5 77 , Mayu S. Jai Malik , Sunayna Choudhary. Natasha Paranjapye , Valerie Daggett. By varying the stress pattern slightly at key moments, you can break up the pattern and make the poem more aurally interesting for the reader, and also use the variation to draw attention to key phrases in your poem. Arms and Interventions.
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Study Start Date: May Actual Primary Completion Date: February Actual Study Completion Date: EGCG administration in Down syndrome patients will result in an improvement of their cognitive performance. Dietary Supplement: Placebo Comparator: Placebo No active substance is given. Placebo No active treatment is given.
Predose baseline and 3 months end of treatment. Secondary Outcome Measures: Predose baseline: Digit Span: Spatial Span SSP: Executive functions will be assessed using the following tests:. Digits Span: Word fluency. Visuomotor coordination will be assessed following the these tests:.
Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below.
For general information, Learn About Clinical Studies. Layout table for eligibility information Ages Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria:. Hide glossary Glossary Study record managers: Search for terms x. Save this study. Warning You have reached the maximum number of saved studies The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
Listing a study does not mean it has been evaluated by the U. Federal Government. Read our disclaimer for details. NCT Recruitment Status: Completed First Posted: July 14, Last Update Posted: March 13, Study Description. There is a mounting evidence of the modulation properties of the major catechin in green tea, epigallocatechingallate EGCG , on dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A gene overexpression in the brains of DS mouse models.
The aims are to investigate the clinical benefits and safety of EGCG administration in young adults with DS, to establish short-term EGCG effects three months on neurocognitive performance, and to determine the persistency or reversibility of EGCG related effects after three months of discontinued use. MedlinePlus related topics: FDA Resources.
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Nyberg , Kirsten Andersen , Anna K. Emotional Health. Dueholm , Brian S. Inclusion Criteria:
Mimi GaoRoland Winter. Just as the Miltonic stanza explores the relationship between parts of the Petrarchan sonnet by using line breaks and enjambments, the Spenserian sonnet explores the relationship between parts of the Shakespearean sonnet by using interlocking rhyme patterns. What should I do? NybergKirsten AndersenAnna K. Placebo No active treatment is given. Exceptions were made for single doses of symptomatic medication administered up to the week preceding the trial.
Talk to Gartner now and learn the benefits of becoming a Gartner client. The terza rima sonnet, though, is written using interlocking tercets, or stanzas of three lines. Completed First Posted: